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Western blot analysis of extracts of HeLa cells, using Phospho-DRP1-S616 antibody (AP0849) at 1:1000 dilution.HeLa cells were treated by Calyculin A (100 nM) at 37℃ for 30 minutes after serum-starvation overnight.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
Phospho-DRP1-S616 Rabbit pAb
Catalog No：AB-AP0849
Manufacturer：ABclonal
Synonyms：DNM1L;DLP1;DRP1;DVLP;DYMPLE;EMPF;EMPF1;HDYNIV
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-DRP1-S616 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer’s disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen: | A synthetic phosphorylated peptide around S616 of human DRP1 (NP_036192.2). |
| Gene ID: | 10059 |
| Swiss prot: | O00429 |
| Molecular weight: | 60kDa/78kDa/79kDa/80kDa/81kDa/82kDa/83kDa |
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