.jpg)
Western blot analysis of extracts of U937 cells, using Phospho-LCP2-Y145 antibody (AP0816) at 1:1000 dilution. U-937 cells were treated by PMA/TPA (200nM) for 30 minutes.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
Phospho-LCP2-Y145 Rabbit pAb
Catalog No：AB-AP0816
Manufacturer：ABclonal
Synonyms：LCP2;SLP-76;SLP76
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-LCP2-Y145 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function. |
| Immunogen: | A synthetic phosphorylated peptide around Y145 of human LCP2 (NP_005556.1). |
| Gene ID: | 3937 |
| Swiss prot: | Q13094 |
| Molecular weight: | 60kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：AB-AP0024
Manufacturer：ABclonal
Synonyms：EGFR;ERBB;ERBB1;HER1;NISBD2;PIG61;mENA
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0016
Manufacturer：ABclonal
Synonyms：CDK1;CDC2;CDC28A;P34CDC2
Applications：WB,IHC,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0015
Manufacturer：ABclonal
Synonyms：CDK1;CDC2;CDC28A;P34CDC2
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0010
Manufacturer：ABclonal
Synonyms：BAD;BBC2;BCL2L8;Bad
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0008
Manufacturer：ABclonal
Synonyms：AT1;ATA;ATC;ATD;ATDC;ATE;TEL1;TELO1;ATM
Applications：WB,IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0005
Manufacturer：ABclonal
Synonyms：AKT2;HIHGHH;PKBB;PKBBETA;PRKBB;RAC-BETA
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00