Western blot analysis of extracts of PC-12 cells, using Phospho-DRP1-S637 antibody (AP0812) at 1:1000 dilution. PC-12 cells were treated by Forskolin (30uM) for 30 minutes.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit (RM00020).|Exposure time: 20s.
Phospho-DRP1-S637 Rabbit pAb
Catalog No:AB-AP0812
Manufacturer:ABclonal
Synonyms:DNM1L;DLP1;DRP1;DVLP;DYMPLE;EMPF;EMPF1;HDYNIV
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-DRP1-S637 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer’s disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen: | A synthetic phosphorylated peptide around S637 of human DRP1 (NP_036192.2). |
Gene ID: | 10059 |
Swiss prot: | O00429 |
Molecular weight: | 60kDa/78kDa/79kDa/80kDa/81kDa/82kDa/83kDa |
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