.jpg)
Western blot analysis of extracts of various cell lines, using Phospho-Lamin A/C-S22 antibody (AP0777) at 1:2000 dilution or Lamin A antibody (A0249). HeLa cells were treated by Hydroxyurea (4 mM) at 37℃ for 20 hours or treated by Paclitaxel (100 nM/mL) at 37℃ for 20 hours. C6 cells were treated by Hydroxyurea (4 mM) at 37℃ for 20 hours or treated by Paclitaxel (100 nM) at 37℃ for 20 hours. |Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 1s.
Phospho-Lamin A/C-S22 Rabbit pAb
Catalog No：AB-AP0777
Manufacturer：ABclonal
Synonyms：LMNA;CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;FPLD2;HGPS;IDC;LDP1;LFP;LGMD1B;LMN1;LMNC;LMNL1;MADA;PRO1;lamin;Lamin A/C
Applications：WB,IP
Reactivity：Human,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-Lamin A/C-S22 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. |
| Immunogen: | A synthetic phosphorylated peptide around S22 of human Lamin A (NP_005563.1). |
| Gene ID: | 4000 |
| Swiss prot: | P02545 |
| Molecular weight: | 62-74kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：AB-AP0024
Manufacturer：ABclonal
Synonyms：EGFR;ERBB;ERBB1;HER1;NISBD2;PIG61;mENA
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0023
Manufacturer：ABclonal
Synonyms：EGFR;ERBB;ERBB1;HER1;NISBD2;PIG61;mENA
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0021
Manufacturer：ABclonal
Synonyms：ADCADN;AIM;CXXC9;DNMT;HSN1E;MCMT;m.HsaI;DNMT1
Applications：WB,IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0017
Manufacturer：ABclonal
Synonyms：CHEK1;CHK1
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0016
Manufacturer：ABclonal
Synonyms：CDK1;CDC2;CDC28A;P34CDC2
Applications：WB,IHC,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
Catalog No：AB-AP0008
Manufacturer：ABclonal
Synonyms：AT1;ATA;ATC;ATD;ATDC;ATE;TEL1;TELO1;ATM
Applications：WB,IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00