Western blot analysis of extracts of HeLa cells, using Phospho-STK11-T189 pAb (AP0603) at 1:1000 dilution or LKB1 antibody (A2122).A-431 cells were treated by 10% FBS for after serum-starvation overnight.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit (RM00020).
Phospho-STK11-T189 Rabbit pAb
Catalog No:AB-AP0603
Manufacturer:ABclonal
Synonyms:LKB1;PJS;hLKB1;STK11
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-STK11-T189 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
Immunogen: | A synthetic phosphorylated peptide around T189 of human STK11 (NP_000446.1). |
Gene ID: | 6794 |
Swiss prot: | Q15831 |
Molecular weight: | 45kDa/48kDa |
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