CLDN12 Rabbit pAb
Catalog No:AB-A10709
Manufacturer:ABclonal
Synonyms:CLDN12
Applications:WB
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | CLDN12 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CLDN12 (NP_001172001.1). |
Gene ID: | 9069 |
Swiss prot: | P56749 |
Molecular weight: | 27kDa |
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