Phospho-B-Raf-S728 Rabbit pAb
Catalog No:AB-AP0576
Manufacturer:ABclonal
Synonyms:BRAF;B-RAF1;B-raf;BRAF1;NS7;RAFB1
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-B-Raf-S728 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
Immunogen: | A synthetic phosphorylated peptide around S728 of human BRAF (NP_004324.2). |
Gene ID: | 673 |
Swiss prot: | P15056 |
Molecular weight: | 84kDa |
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