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Western blot analysis of extracts of HepG2 cells, using Phospho-PDGFRA-Y849 antibody (AP0569) at 1:1000 dilution. HepG2 cells were treated by EGF (100ng/mL) for 30 minutes after serum-starvation overnight.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
Phospho-PDGFRA-Y849 Rabbit pAb
Catalog No：AB-AP0569
Manufacturer：ABclonal
Synonyms：PDGFRA;CD140A;PDGFR-2;PDGFR2;GAS9;RHEPDGFRA
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-PDGFRA-Y849 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. |
| Immunogen: | A synthetic phosphorylated peptide around Y849 of human PDGFRA (NP_006197.1). |
| Gene ID: | 5156 |
| Swiss prot: | P16234 |
| Molecular weight: | 24kDa/82kDa/122kDa |
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