Phospho-Tyk2-Y292 Rabbit pAb
Catalog No：AB-AP0565
Manufacturer：ABclonal
Synonyms：TYK2;IMD35;JTK1
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-Tyk2-Y292 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) – a primary immunodeficiency characterized by elevated serum immunoglobulin E. |
| Immunogen: | A synthetic phosphorylated peptide around Y292 of human Tyk2 (NP_003322.3). |
| Gene ID: | 7297 |
| Swiss prot: | P29597 |
| Molecular weight: | 133kDa |
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