Phospho-PDGFRB-Y740 Rabbit pAb
Catalog No:AB-AP0556
Manufacturer:ABclonal
Synonyms:CD140B;IBGC4;IMF1;JTK12;KOGS;PDGFR;PDGFR-1;PDGFR1;PENTT;PDGF Receptor beta;PDGFRB;PDGFR beta
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-PDGFRB-Y740 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. |
Immunogen: | A synthetic phosphorylated peptide around Y740 of human PDGFRB (NP_002600.1). |
Gene ID: | 5159 |
Swiss prot: | P09619 |
Molecular weight: | 37kDa/123kDa |
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