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Western blot analysis of extracts of NIH/3T3 cells, using Phospho-Tyk2-Y1054/1055 Rabbit pAb (AP0543) at 1:1000 dilution.NIH/3T3 cells were treated by IFN-ɑ (100 ng/ml) at 37℃ for 30 minutes after serum-starvation overnight.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 180s.
Phospho-Tyk2-Y1054/1055 Rabbit pAb
Catalog No：AB-AP0543
Manufacturer：ABclonal
Synonyms：TYK2;IMD35;JTK1
Applications：WB
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-Tyk2-Y1054/1055 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) – a primary immunodeficiency characterized by elevated serum immunoglobulin E. |
| Immunogen: | A synthetic phosphorylated peptide around Y1054 & Y1055 of human Tyk2 (NP_003322.3). |
| Gene ID: | 7297 |
| Swiss prot: | P29597 |
| Molecular weight: | 133kDa |
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