Western blot analysis of extracts of NIH/3T3 cells, using Phospho-RB-S780 antibody (AP0444) at dilution.NIH/3T3 cells were treated by UV at room temperature for 15-30 minutes.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
Phospho-RB-S780 Rabbit pAb
Catalog No:AB-AP0444
Manufacturer:ABclonal
Synonyms:OSRC;PPP1R130;RB;p105-Rb;pRb;pp110;RB1;Rb
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-RB-S780 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
Immunogen: | A phospho specific peptide corresponding to residues surrounding S780 of human RB |
Gene ID: | 5925 |
Swiss prot: | P06400 |
Molecular weight: | 106kDa |
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