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Western blot analysis of extracts from 293 cells untreated or treated with EGF using Phospho-HDAC4-S246/HDAC5-S259/HDAC9-S220 Antibody (AP0280).|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
Phospho-HDAC4-S246/HDAC5-S259/HDAC9-S220 Rabbit pAb
Catalog No：AB-AP0280
Manufacturer：ABclonal
Synonyms：HDAC4/HDAC5/HDAC9
Applications：WB,IHC
Reactivity：Human
Host：Rabbit
Conjugate：No
€150,00 – €410,00
| Product Name: | Phospho-HDAC4-S246/HDAC5-S259/HDAC9-S220 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008] |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding S246 of human HDAC4 |
| Gene ID: | 9759/10014/9734 |
| Swiss prot: | P56524/Q9UQL6/Q9UKV0 |
| Molecular weight: | 57-65kDa/97-122kDa |
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