Western blot analysis of extracts of mouse brain, using Phospho-CAMK2A-T286 antibody (AP0255) at 1:1000 dilution. Mouse brain cell lysates were treated by CIP at 37°C for 1 hour.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
Phospho-Camk2a-T286 Rabbit pAb
Catalog No:AB-AP0255
Manufacturer:ABclonal
Synonyms:CAMK2A;CAMKA
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-Camk2a-T286 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. |
Immunogen: | A phospho specific peptide corresponding to residues surrounding T286 of human Camk2a |
Gene ID: | 815 |
Swiss prot: | Q9UQM7 |
Molecular weight: | 22kDa/54kDa |
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