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Western blot analysis of extracts from HeLa cells using Phospho-eIF4EBP1-T45 antibody (AP0219).|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
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Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-eIF4EBP1-T45 antibody (AP0219).
Phospho-eIF4EBP1-T45 Rabbit pAb
Catalog No：AB-AP0219
Manufacturer：ABclonal
Synonyms：4E-BP1;4EBP1;BP-1;PHAS-I;EIF4EBP1
Applications：WB,IHC
Reactivity：Human
Host：Rabbit
Conjugate：No
€150,00 – €410,00
| Product Name: | Phospho-eIF4EBP1-T45 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding T45 of human Phospho-eIF4EBP1-T45 |
| Gene ID: | 1978 |
| Swiss prot: | Q13541 |
| Molecular weight: | 12kDa |
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