Western blot analysis of extracts of Jurkat cells, using Phospho-MAX-S11 antibody (AP0072) at 1:1000 dilution. Jurkat cells were treated by serum-starvation overnight.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.
Phospho-MAX-S11 Rabbit pAb
Catalog No:AB-AP0072
Manufacturer:ABclonal
Synonyms:MAX;bHLHd4
Applications:WB,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €410,00
Product Name: | Phospho-MAX-S11 Rabbit pAb |
Category: | Phosphorylated Antibodies |
Description: | The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. |
Immunogen: | A synthetic phosphorylated peptide around S11 of human MAX (NP_002373.3). |
Gene ID: | 4149 |
Swiss prot: | P61244 |
Molecular weight: | 9kDa/11kDa/12kDa/15kDa/17kDa/18kDa |
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