Phospho-Insulin Receptor-Y1345 Rabbit pAb
Catalog No：AB-AP0046
Manufacturer：ABclonal
Synonyms：CD220;HHF5;INSR
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-Insulin Receptor-Y1345 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Y1345 of human INSR |
| Gene ID: | 3643 |
| Swiss prot: | P06213 |
| Molecular weight: | 155kDa/156kDa |
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