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Immunofluorescence analysis of MCF-7 cells using Phospho-DNMT1-pY399 antibody (AP0022). Blue: DAPI for nuclear staining.
Phospho-DNMT1-pY399 Rabbit pAb
Catalog No：AB-AP0022
Manufacturer：ABclonal
Synonyms：ADCADN;AIM;CXXC9;DNMT;HSN1E;MCMT;m.HsaI;DNMT1
Applications：WB,IF
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-DNMT1-pY399 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. |
| Immunogen: | A synthetic phosphorylated peptide around Y399 of human Phospho-DNMT1-pY399 (NP_001370.1). |
| Gene ID: | 1786 |
| Swiss prot: | P26358 |
| Molecular weight: | 144kDa/183kDa/184kDa |
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