Phospho-Bad-S112 Rabbit pAb
Catalog No：AB-AP0010
Manufacturer：ABclonal
Synonyms：BAD;BBC2;BCL2L8;Bad
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €410,00
| Product Name: | Phospho-Bad-S112 Rabbit pAb |
| Category: | Phosphorylated Antibodies |
| Description: | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding S112 of human Bad |
| Gene ID: | 572 |
| Swiss prot: | Q92934 |
| Molecular weight: | 18kDa |
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