Western blot analysis of extracts of various cell lines, using JARID2 antibody (A9823) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
JARID2 Rabbit pAb
Catalog No:AB-A9823
Manufacturer:ABclonal
Synonyms:JARID2;JMJ
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | JARID2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1027-1246 of human JARID2 (NP_004964.2). |
Gene ID: | 3720 |
Swiss prot: | Q92833 |
Molecular weight: | 106kDa/119kDa/138kDa |
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