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Western blot analysis of extracts of Rat eye, using RPA70 Rabbit mAb (A9615) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
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Immunohistochemistry of paraffin-embedded rat retina using RPA70 Rabbit mAb (A9615) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse retina using RPA70 Rabbit mAb (A9615) at dilution of 1:100 (40x lens).
RPA70 Rabbit mAb
Catalog No：AB-A9615
Manufacturer：ABclonal
Synonyms：BCO3, LCA2, RP20, mRPE65, rd12, sRPE65
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | RPA70 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq, Jul 2008] |
| Immunogen: | A synthesized peptide derived from human RPA70 |
| Gene ID: | 6121 |
| Swiss prot: | Q16518 |
| Molecular weight: | 61kDa |
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