RFXAP Rabbit pAb
Catalog No:AB-A9411
Manufacturer:ABclonal
Synonyms:RFXAP
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | RFXAP Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human RFXAP (NP_000529.1). |
Gene ID: | 5994 |
Swiss prot: | O00287 |
Molecular weight: | 28kDa |
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