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Western blot analysis of extracts of various cell lines, using SNX15 antibody (A9158) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
SNX15 Rabbit pAb
Catalog No：AB-A9158
Manufacturer：ABclonal
Synonyms：SNX15;HSAF001435
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SNX15 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human SNX15 (NP_037438.2). |
| Gene ID: | 29907 |
| Swiss prot: | Q9NRS6 |
| Molecular weight: | 29kDa/38kDa |
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