UBA7 Rabbit pAb
Catalog No：AB-A9142
Manufacturer：ABclonal
Synonyms：UBA7;D8;UBA1B;UBE1L;UBE2
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €325,00
| Product Name: | UBA7 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 723-1012 of human UBA7 (NP_003326.2). |
| Gene ID: | 7318 |
| Swiss prot: | P41226 |
| Molecular weight: | 111kDa |
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