Western blot analysis of extracts of various cell lines, using CNOT7 antibody (A8959) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
CNOT7 Rabbit pAb
Catalog No:AB-A8959
Manufacturer:ABclonal
Synonyms:CNOT7;CAF-1;CAF1;Caf1a;hCAF-1
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CNOT7 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-160 of human CNOT7 (NP_037486.2). |
Gene ID: | 29883 |
Swiss prot: | Q9UIV1 |
Molecular weight: | 28kDa/32kDa |
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