Western blot analysis of extracts of mouse kidney, using KCNJ1 antibody (A8554) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
KCNJ1 Rabbit pAb
Catalog No:AB-A8554
Manufacturer:ABclonal
Synonyms:KCNJ1;KIR1.1;ROMK;ROMK1
Applications:WB,IHC
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | KCNJ1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 182-391 of human KCNJ1 (NP_000211.1). |
Gene ID: | 3758 |
Swiss prot: | P48048 |
Molecular weight: | 42kDa/44kDa |
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