Western blot analysis of extracts of various cell lines, using MS4A2 Antibody (A8543) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
MS4A2 Rabbit pAb
Catalog No:AB-A8543
Manufacturer:ABclonal
Synonyms:MS4A2;APY;ATOPY;FCER1B;FCERI;IGEL;IGER;IGHER;MS4A1
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MS4A2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MS4A2 (NP_000130.1). |
Gene ID: | 2206 |
Swiss prot: | Q01362 |
Molecular weight: | 26kDa |
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