ABCB11 Rabbit pAb
Catalog No:AB-A8467
Manufacturer:ABclonal
Synonyms:ABCB11;ABC16;BRIC2;BSEP;PFIC-2;PFIC2;PGY4;SPGP
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ABCB11 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-750 of human ABCB11 (NP_003733.2). |
Gene ID: | 8647 |
Swiss prot: | O95342 |
Molecular weight: | 146kDa |
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