Western blot analysis of extracts of mouse pancreas, using HRG antibody (A8431) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
HRG Rabbit pAb
Catalog No:AB-A8431
Manufacturer:ABclonal
Synonyms:HRG;HPRG;HRGP;THPH11
Applications:WB,IHC
Reactivity:Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | HRG Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein’s effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-260 of human HRG (NP_000403.1). |
Gene ID: | 3273 |
Swiss prot: | P04196 |
Molecular weight: | 59kDa |
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