Western blot analysis of extracts of MCF-7 cells, using Glucosylceramidase beta (Glucosylceramidase beta (GBA)) antibody (A8420) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
Glucosylceramidase beta (GBA) Rabbit pAb
Catalog No:AB-A8420
Manufacturer:ABclonal
Synonyms:GBA;GBA1;GCB;GLUC
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Glucosylceramidase beta (GBA) Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human Glucosylceramidase beta (Glucosylceramidase beta (GBA)) (NP_000148.2). |
Gene ID: | 2629 |
Swiss prot: | P04062 |
Molecular weight: | 29kDa/50kDa/54kDa/57kDa/59kDa |
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