Western blot analysis of extracts of various cell lines, using Desmoglein 3 antibody (A8412) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
Desmoglein 3 Rabbit pAb
Catalog No:AB-A8412
Manufacturer:ABclonal
Synonyms:DSG3;CDHF6;PVA
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Desmoglein 3 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 749-999 of human Desmoglein 3 (NP_001935.2). |
Gene ID: | 1830 |
Swiss prot: | P32926 |
Molecular weight: | 107kDa |
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