Western blot analysis of extracts of various cell lines, using P2RX7 antibody (A10511) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
P2RX7 Rabbit pAb
Catalog No:AB-A10511
Manufacturer:ABclonal
Synonyms:P2RX7;P2X7
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | P2RX7 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 47-334 of human P2RX7 (NP_002553.3). |
Gene ID: | 5027 |
Swiss prot: | Q99572 |
Molecular weight: | 14kDa/31kDa/35kDa/41kDa/49kDa/58kDa/68kDa |
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