Western blot analysis of extracts of Mouse testis, using RSPO1 antibody (A8289) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
RSPO1 Rabbit pAb
Catalog No:AB-A8289
Manufacturer:ABclonal
Synonyms:RSPO1;CRISTIN3;RSPO
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | RSPO1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-263 of human RSPO1 (NP_001033722.1). |
Gene ID: | 284654 |
Swiss prot: | Q2MKA7 |
Molecular weight: | 21kDa/25kDa/28kDa |
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