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Western blot analysis of extracts of various cell lines, using SOST antibody (A8213) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 30s.
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Immunohistochemistry of paraffin-embedded human prostate using SOST antibody (A8213) at dilution of 1:100 (40x lens).
SOST Rabbit pAb
Catalog No：AB-A8213
Manufacturer：ABclonal
Synonyms：SOST;CDD;DAND6;SOST1;VBCH
Applications：WB,IHC
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SOST Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-213 of human SOST (NP_079513.1). |
| Gene ID: | 50964 |
| Swiss prot: | Q9BQB4 |
| Molecular weight: | 24kDa |
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