Western blot analysis of extracts of various cell lines, using MBNL1 antibody (A8054) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
MBNL1 Rabbit pAb
Catalog No:AB-A8054
Manufacturer:ABclonal
Synonyms:MBNL1;EXP;MBNL
Applications:WB,IHC,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MBNL1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-382 of human MBNL1 (NP_066368.2). |
Gene ID: | 4154 |
Swiss prot: | Q9NR56 |
Molecular weight: | 33kDa/34kDa/36kDa/37kDa/39kDa/40kDa/41kDa |
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