TDP1 Rabbit pAb
Catalog No:AB-A7984
Manufacturer:ABclonal
Synonyms:TDP1
Applications:IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TDP1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TDP1 (NP_060789.2). |
Gene ID: | 55775 |
Swiss prot: | Q9NUW8 |
Molecular weight: | 41kDa/68kDa |
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