Western blot analysis of extracts of mouse brain, using ARHGEF11 antibody (A7954) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
ARHGEF11 Rabbit pAb
Catalog No:AB-A7954
Manufacturer:ABclonal
Synonyms:ARHGEF11;GTRAP48;PDZ-RHOGEF
Applications:WB,IHC
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ARHGEF11 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. |
Immunogen: | A synthetic peptide of human ARHGEF11 |
Gene ID: | 9826 |
Swiss prot: | O15085 |
Molecular weight: | 167kDa/172kDa |
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