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Western blot analysis of extracts of 22Rv1 cells, using ARTN antibody (A7949) at 1:500 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 30s.
ARTN Rabbit pAb
Catalog No：AB-A7949
Manufacturer：ABclonal
Synonyms：ARTN;ART;ENOVIN;EVN;NBN;artemin
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | ARTN Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. |
| Immunogen: | A synthetic peptide of human ARTN |
| Gene ID: | 9048 |
| Swiss prot: | Q5T4W7 |
| Molecular weight: | 22kDa/23kDa/24kDa |
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