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Western blot analysis of extracts of rat spinal cord, using RGR antibody (A7925) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
RGR Rabbit pAb
Catalog No：AB-A7925
Manufacturer：ABclonal
Synonyms：RGR;RP44
Applications：WB
Reactivity：Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | RGR Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 156-295 of human RGR (NP_002912.2). |
| Gene ID: | 5995 |
| Swiss prot: | P47804 |
| Molecular weight: | 27kDa/31kDa/32kDa |
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