Western blot analysis of extracts of various cell lines, using Filamin A antibody (A7896) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 30s.
Filamin A Rabbit pAb
Catalog No:AB-A7896
Manufacturer:ABclonal
Synonyms:FLNA;ABP-280;ABPX;CSBS;CVD1;FLN;FLN-A;FLN1;FMD;MNS;NHBP;OPD;OPD1;OPD2;XLVD;XMVD;filamin-A
Applications:WB,IHC
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | Filamin A Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 2500 to the C-terminus of human Filamin A (NP_001104026.1). |
Gene ID: | 2316 |
Swiss prot: | P21333 |
Molecular weight: | 280kDa |
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