Western blot analysis of extracts of various cell lines, using CHRNG antibody (A7884) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10001 dilution.|Lysates/proteins: 26ug per lane.|Blocking buffer: 4% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3s.
CHRNG Rabbit pAb
Catalog No:AB-A7884
Manufacturer:ABclonal
Synonyms:CHRNG;ACHRG
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CHRNG Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 328-517 of human CHRNG (NP_005190.4). |
Gene ID: | 1146 |
Swiss prot: | P07510 |
Molecular weight: | 52kDa/57kDa |
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