Western blot analysis of extracts of various cell lines, using CHRND antibody (A10467) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
CHRND Rabbit pAb
Catalog No:AB-A10467
Manufacturer:ABclonal
Synonyms:CHRND;ACHRD;CMS2A;CMS3A;CMS3B;CMS3C;FCCMS;SCCMS
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CHRND Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human CHRND (NP_000742.1). |
Gene ID: | 1144 |
Swiss prot: | Q07001 |
Molecular weight: | 57kDa/58kDa |
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