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Western blot analysis of extracts of various cell lines, using RBFOX1 antibody (A7811) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
RBFOX1 Rabbit pAb
Catalog No：AB-A7811
Manufacturer：ABclonal
Synonyms：RBFOX1;2BP1;A2BP1;FOX-1;FOX1;HRNBP1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | RBFOX1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human RBFOX1 (NP_665900.1). |
| Gene ID: | 54715 |
| Swiss prot: | Q9NWB1 |
| Molecular weight: | 40kDa/42kDa/44kDa |
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