Western blot analysis of extracts of various cell lines, using CD2AP antibody (A7788) at 1:500 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 60s.
CD2AP Rabbit pAb
Catalog No:AB-A7788
Manufacturer:ABclonal
Synonyms:CD2AP;CMS
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CD2AP Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. |
Immunogen: | A synthetic peptide of human CD2AP |
Gene ID: | 23607 |
Swiss prot: | Q9Y5K6 |
Molecular weight: | 71kDa |
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