Western blot analysis of extracts of various cell lines, using CYP11B1 antibody (A7664) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
CYP11B1 Rabbit pAb
Catalog No:AB-A7664
Manufacturer:ABclonal
Synonyms:CYP11B1;CPN1;CYP11B;FHI;P450C11
Applications:WB
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CYP11B1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B1 (NP_000488.3). |
Gene ID: | 1584 |
Swiss prot: | P15538 |
Molecular weight: | 49kDa/57kDa |
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