.jpg)
Western blot analysis of extracts of various cell lines, using TYMS antibody (A10441) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 1s.
.jpg)
Western blot analysis of extracts of various cell lines, using TYMS antibody (A10441) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
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Immunohistochemistry of paraffin-embedded mouse spleen using TYMS Rabbit pAb (A10441) at dilution of 1:100 (40x lens).
TYMS Rabbit pAb
Catalog No：AB-A10441
Manufacturer：ABclonal
Synonyms：TYMS;HST422;TMS;TS
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | TYMS Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human TYMS (NP_001062.1). |
| Gene ID: | 7298 |
| Swiss prot: | P04818 |
| Molecular weight: | 26kDa/31kDa/35kDa |
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