Western blot analysis of extracts of various cell lines, using OX40 antibody (A7499) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 30s.
OX40 Rabbit pAb
Catalog No:AB-A7499
Manufacturer:ABclonal
Synonyms:TNFRSF4;ACT35;CD134;IMD16;OX40;TXGP1L
Applications:WB
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | OX40 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-214 of human OX40 (NP_003318.1). |
Gene ID: | 7293 |
Swiss prot: | P43489 |
Molecular weight: | 29kDa |
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