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Western blot analysis of extracts of various cell lines, using COQ3 antibody (A7469) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded mouse brain using COQ3 antibody (A7469) at dilution of 1:100 (40x lens).
COQ3 Rabbit pAb
Catalog No：AB-A7469
Manufacturer：ABclonal
Synonyms：COQ3;DHHBMT;DHHBMTASE;UG0215E05;bA9819.1;coenzyme Q3
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | COQ3 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008] |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-369 of human COQ3 (NP_059117.3). |
| Gene ID: | 51805 |
| Swiss prot: | Q9NZJ6 |
| Molecular weight: | 41kDa |
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