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Western blot analysis of extracts of various cell lines, using LFNG antibody (A7441) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 30s.
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Immunohistochemistry of paraffin-embedded human stomach using LFNG antibody (A7441) at dilution of 1:100 (40x lens).
LFNG Rabbit pAb
Catalog No：AB-A7441
Manufacturer：ABclonal
Synonyms：LFNG;SCDO3;beta-1
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | LFNG Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human LFNG (NP_002295.1). |
| Gene ID: | 3955 |
| Swiss prot: | Q8NES3 |
| Molecular weight: | 28kDa/35kDa/39kDa/41kDa |
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