Western blot analysis of extracts of various cell lines, using PHF6 antibody (A7393) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 90s.
PHF6 Rabbit pAb
Catalog No:AB-A7393
Manufacturer:ABclonal
Synonyms:BFLS;BORJ;CENP-31;PHF6
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | PHF6 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-312 of human PHF6 (NP_115711.2). |
Gene ID: | 84295 |
Swiss prot: | Q8IWS0 |
Molecular weight: | 35kDa/37kDa/41kDa |
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